Clinical Research is all investigation performed with the help of patients in hospital or other clinical setting. The purpose is generally to improve the diagnostic tools which are yet poor in the field of psychiatric and behavioral diseases. Only by a deeper investigation potency - in the field of biomarker and/or in the field of tomographic imaging - we can hope to promote better definition and hence better detection of the various facets inherent to psychiatric and behavioral diseases.

Supported Public Project: ADHD-sythe.

The present project is aimed at establishing evidence-based diagnostic criteria for ADHD, in the field of biomarker and/or in the field of tomographic imaging. There are also two main "preclinical" goals, aimed at basic neurobiology of ADHD, whose progress you can track !!!

This project will achieve these CLINICAL goals: 1) to assess levels of DAT / SERT aAbs in plasma samples from ADHD children, thus establishing a potential role for auto-immune processes in human ADHD; 2) to perform magnetic resonance (MR) measures in brains of both ADHD childrens and animal models, to draw possible correlations. See the workplan (IT).

Goal 1) Clinicians are now taking "baseline" blood samples between first arrival of children and decision to start therapy (a period normally lasting a week or two). Then, a second sampling after 1-2 months : this second sample will be identified as coming from a RESPONDER to therapy vs the NON RESPONDERS to therapy, plus a NON-DRUG THERAPY group. Ritalin is usually efficient after two-three weeks of therapy. The final goal is to collect up to 50 samples from pure ADHD children under (Ritalin) treatment. 

THE ADVERTISEMENT OF OUR PUTATIVE DIAGNOSTIC DISCOVERIES WILL BE PLACED HERE.