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Clinical Care & Knowledge on: ADHD, OCD, Tourette's

Clinical Research is all investigation performed with the help of patients in hospital or other clinical setting. The purpose is generally to improve the diagnostic tools which are yet poor in the field of psychiatric and behavioral diseases. Only by a deeper investigation potency - in the field of biomarker and/or in the field of tomographic imaging - we can hope to promote better definition and hence better detection of the various facets inherent to psychiatric and behavioral diseases. Clinical Care should always be based on UP-to-DATE CLINICAL KNOWLEDGE... EMMA is fully committed to divulge rapidly all novel discoveries in the field of mind and metabolism, with a special regard on ADHD, Obsessive-Compulsive Disorder, and Tourette Syndrome.

In this Section, you will find publications we suggest to read. BROWSE this Section using the buttons "next" AND "prev" at footer of pages. Next >


Sealed MR Imaging-Detectable Metabolic Alterations in Attention Deficit/Hyperactivity Disorder: From Preclinical to Clinical Studies. (2014) By: Altabella L, Zoratto F, Adriani W, Canese R. Journal: AJNR Am. J. Neuroradiol. - Read through AJNR website

Tongue out Apr 28, 2009 - Altered anandamide degradation in attention-deficit / hyperactivity disorder. By: Centonze D., ..., Curatolo P., Maccarrone M. Journal: Neurology     

ADHD : suggested multiple susceptibility genes

Guan et al., Molecular Psychiatry (2009) 14: 546–554 To read click here 


Attention deficit hyperactivity disorder (ADHD) is a common childhood-onset behavioral disorder with a definite genetic component. The search for genes predisposing to ADHD has focused on genes involved in the regulation of monoamine systems. (...) Additionally, the most interesting news: for six genes (SNAP25NET1DBHCHRNA4, DRD3 and SYT1) we detected one or more SNPs with nominal P-valuesless than or equal to0.05. This study has identified several genes as promising susceptibility loci for ADHD. Replication efforts and further investigations remain necessary to provide definite proof of association.

Volume 65 (1 April 2009) of "Biological Psychiatry" is entirely devoted to ADHD :  
click here to read in full - Attention Deficit / Hyperactivity Disorder: From Circuit Dysfunction to Novel Treatments



Full Text: HTMLPDF (Size: 158K)  

Working toward a neurobiological account of ADHD: Commentary on Gail Tripp and Jeff Wickens, Dopamine transfer deficit
by Jonathan Williams, Gatsby Computational Neuroscience Unit, University College London, UK 

Evidence of Developmental Alterations in Cortical and Subcortical Regions of Children With Attention-Deficit / Hyperactivity Disorder. Multivoxel In Vivo Phosphorus 31 Spectroscopy. Arch Gen Psychiatry. 2008;65(12):1419-1428.

An interesting paper on 31-P MRS as diagnostic tool (click to read)

Brain Dev. 2012 Sep; 34(8): 667-73. Epub 2011 Dec 16.

Long term clinical course of Tourette syndrome.

Rizzo R, Gulisano M, Calo' PV, Curatolo P.

Brain Dev. 2007 Aug; 29(7): 413-20. Epub 2007 Feb 05.

Disentangling the effects of Tourette syndrome and attention deficit / hyperactivity disorder on cognitive and behavioral phenotypes.

Rizzo R, Curatolo P, Gulisano M, Virzi' M, Arpino C, Robertson MM.  


All NEWS announced by EMMA before February 2009 can be found in our HISTORICAL ARCHIVE. 

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the 13th Dresden Symposium on Autoantibodies in September 2017


Debates & Lessons
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Beyond science: philosophy, mind and metabolism:
1) Genes, but ...NOT ONLY...

2) Latest hints on innovation: "ALTERNATIVE MEDICINES"

3) The burden of ADHD on modern society (families, health systems).
Societies, Journals (to visit)

Science Societies, Science Journals.

Associations to help people with a psychiatric disease (and their families).


Which of these lotteries would you bet a stake on?
Who shall be the new Directive Committee member?